MRC Protein Phosphorylation and Ubiquitylation Unit

The MRCPPU CRISPR facility has a wealth of experience with >900 successful projects completed over the past 5 years comprising KOs and KIs in a variety of cell types including standard adherent cancer lines, mouse ES cells, and human iPSCs.
Let us take care of your routine cloning allowing you to focus on your research. We will work with you to clone your gene of interest into your vector of choice. Our highly qualified cloners have years of experience and are committed to providing the best service possible.
Established in 1998, we are a core DNA sequencing and fragment analysis facility based within the Medical Research Council Protein Phosphorylation and Ubiquitylation Unit (MRC PPU) in Dundee, Scotland.
We have developed a sensitive and fast assay to quantify in vitro DUB enzyme activity using matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry.
The MRC Protein Phosphorylation and Ubiquitylation Unit at The University of Dundee pioneered analysis of the selectivity of protein kinase inhibitors by setting up the first service to tackle this problem in 1998.

MRC Centre for Virus Research

The CVR, with support from LifeArc and the MRC, has established a translational facility for antiviral drug screening and resistance development. CRUSH (COVID-19 Resistance and Drug-Screening Hub) is a fully integrated hub with the biocontainment facilities and expertise to support pre-clinical studies of high consequence viruses, including SARS-CoV-2.

MRC Human Genetics Unit

The MRC Human Genetics Unit co-hosts the Edinburgh Super-resolution Imaging Consortium (ESRIC). ESRIC is a national super-resolution imaging facility with a focus on interdisciplinary collaboration and training, offering access to wide variety of super-resolution microscope systems.
The MRC Human Genetucs Unit QTL (Quantitative Trait Locus) in Health and Disease programme has recruited thousands of people to its Scottish and Croatian cohorts. Their special population structures help to improve biological understanding of the causes of variation in complex traits.

Centre for Regenerative Medicine

The CRM Imaging Facility provides microscopes and equipment for imaging live and fixed samples as well as data analysis. This service is supported by a dedicated facility manager.
The Flow and Genomic Cytometry Core Facility provides comprehensive services and assistance in multi-parameter flow cytometry, FACS, single-cell genomic and transcriptomic analysis for both internal and external users.
The CRM High Content Screening facility contains equipment for assay development (throughput and miniaturisation), high throughput imaging and subsequent high content data analysis.

MRC/CSO Social and Public Health Sciences Unit

The Population Health Research Facility (PHRF) offers expert, tailored support to researchers working within community and NHS settings. We provide practical help with every aspect of a study, from the initial funding application through project set-up and management, to final archiving.